Many games are very non-linear and feature extensive stories and morals to them, affecting choices for players to make over the course of the games.

The villains here have multiple possible fates that are affected by player actions. For instance they might be Deceased, Redeemed, Unseen, etc. The villains can also be Protagonists and depending on your actions, they can become Good, Evil, or anywhere in between.

The only way these Villains can be Karma Houndinis is if the karmic escape is the official canonical ending or they have a composited profile of themselves, otherwise they cannot be classified as Karma Houdinis if there are multiple endings and/or alternate scenarios unless Villains do not receive punishment in any of them. In addition, villains in video games that do not include the players' actions cannot count for obvious reasons.